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TOPIC: BioinformaticsClear

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Patrick Gillevet

Associate Professor in the Department of Environmental Science and Policy

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Expertise: Molecular Environmental Biology, Bioinformatics, Molecular Evolution, Genomics, Crohn’s Disease, Breast Cancer, Inflammatory Bowel Disease, Cirrhosis of the Liver and HIV

Gillevet has been the lead scientist at the Environmental Biocomplexity and Ecology group at George Mason University since 1996. This group focuses on using state-of-the-art molecular techniques to study problems in molecular environmental sciences and genomic evolution. Gillevet is also the director of Mason’s new MicroBiome Analysis Center where he and his team of researchers are studying bacteria, viruses, fungi and protozoa within the human body. The effect of these organisms on human health will be a major focus of research at the center where investigators will explore microbial imbalances on or within the gut, mouth, respiratory tract and urinary and reproductive systems.

Prior to joining Mason, Gillevet was the technical director of the University of Illinois’ Center for Prokaryotic Genome Analysis from 1988 to 1990 and served as the director of Harvard University’s Harvard Genome Laboratory from 1990 to 1993. He established an integrated fluorescent sequencing facility at the National Center for Human Genome Research from 1993 to 1996. Gillevet holds a doctorate in biochemistry from the University of Manitoba. His research interests include molecular environmental biology, molecular evolution, genomics, Crohn’s Disease, and bioinformatics.

Media Contact: Michele McDonald, 703-993-8781, mmcdon15@gmu.edu

Donald Seto

Associate Professor of Microbial Genomics, Diversity and Bioinformatics

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Expertise: Bioinformatics, Genome Analysis, Genomics, Adenovirus, Biochemistry, DNA sequencing, Biodetection

Seto is an associate professor in Mason’s Department of Bioinformatics and Computational Biology specializing in microbial and viral genomics. He recently collaborated with the University of Hong Kong, Guangzhou Children’s Hospital, the South China Institute of Technology and the Graduate School of Chinese Academy of Sciences to develop a DNA-based vaccine that has effectively protected mice from the human adenovirus type-3 which is also known as the “uncommon cold.” In addition to his post at Mason, Seto was concurrently a scientific advisor to the USAF Surgeon General and the Director of molecular diagnostics for the USAF-EOS program. His research interests include bioinformatics, genome analysis, genomics, biochemistry, DNA sequencing, and biodetection.

Seto’s lab team is currently focusing on the genomic and bioinformatics analysis of adenovirus genomes, with an interest in mechanisms of molecular evolution of these virus pathogens. In addition, his lab is working on software tools development for whole genome data mining and analyses. A current collaboration with scientists from Canada and Belgium is using these tools to sort out bacteriophage taxonomy. He also has expertise in nucleic acids core facilities development, operations and management. Prior to joining Mason, Seto was involved in several biotech companies as well as a pharmaceutical company, immediately after a position at the National Institutes of Health. He earned a doctorate in biology from The Johns Hopkins University and was a postdoctorate fellow with Dr. Leroy Hood at the California Institute of Technology.

Media Contact: Michele McDonald, 703-993-8781, mmcdon15@gmu.edu